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Manganese Transport via the Transferrin Mechanism

Excessive manganese (Mn) uptake by brain cells, particularly in regions like the basal ganglia, can lead to toxicity. Mn(2+) is transported into cells via a number of mechanisms, while Mn(3+) is believed to be transported similarly to iron (Fe) via the transferrin (Tf) mechanism. Cellular Mn uptake...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gunter, Thomas E., Gerstner, Brent, Gunter, Karlene K., Malecki, Jon, Gelein, Robert, Valentine, William M., Aschner, Michael, Yule, David I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576891/
https://ncbi.nlm.nih.gov/pubmed/23146871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2012.10.018
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