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Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms

Manganese (Mn) is an essential trace element, serving as a cofactor for several key enzymes, such as glutamine synthetase, arginase, pyruvate decarboxylase, and mitochondrial superoxide dismutase. However, its chronic overexposure can result in a neurological disorder referred to as manganism, prese...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Nyarko-Danquah, Ivan, Pajarillo, Edward, Digman, Alexis, Soliman, Karam F. A., Aschner, Michael, Lee, Eunsook
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763224/
https://ncbi.nlm.nih.gov/pubmed/33322668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25245880
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