Evidence for compensatory upregulation of expressed X-linked genes in mammals, Caenorhabditis elegans and Drosophila melanogaster

Many animal species use a chromosome-based mechanism of sex determination, which has led to the coordinate evolution of dosage-compensation systems. Dosage compensation not only corrects the imbalance in the number of X chromosomes between the sexes but also is hypothesized to correct dosage imbalan...

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Hauptverfasser: Deng, Xinxian, Hiatt, Joseph B, Nguyen, Di Kim, Ercan, Sevinc, Sturgill, David, Hillier, LaDeana W, Schlesinger, Felix, Davis, Carrie A, Reinke, Valerie J, Gingeras, Thomas R, Shendure, Jay, Waterston, Robert H, Oliver, Brian, Lieb, Jason D, Disteche, Christine M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576853/
https://ncbi.nlm.nih.gov/pubmed/22019781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.948
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