Chargement en cours...
DNAzyme Footprinting: Detecting Protein-Aptamer Complexation on Surfaces by Blocking DNAzyme Cleavage Activity
A novel method to quantitatively measure the binding of 1proteins to single-stranded DNA (ssDNA) aptamers that employs the inhibition of the DNAzyme hydrolysis of aptamer monolayers is described. A 28-base DNAzyme was designed to specifically bind to and cleave a 29-base ssDNA sequence that can fold...
Enregistré dans:
| Auteurs principaux: | , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3576845/ https://ncbi.nlm.nih.gov/pubmed/23351044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311367t |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|