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Detection of Protein Biomarkers using RNA Aptamer Microarrays and Enzymatically Amplified SPR Imaging

A methodology for the detection of protein biomarkers at picomolar concentrations that utilizes surface plasmon resonance imaging (SPRI) measurements of RNA aptamer microarrays is developed. The adsorption of proteins onto the RNA microarray is detected by the formation of a surface aptamer-protein-...

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Bibliographic Details
Main Authors: Li, Yuan, Lee, Hye Jin, Corn, Robert M.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515860/
https://ncbi.nlm.nih.gov/pubmed/17263339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac061849m
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