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Using genome-wide complex trait analysis to quantify ‘missing heritability’ in Parkinson's disease

Genome-wide association studies (GWASs) have been successful at identifying single-nucleotide polymorphisms (SNPs) highly associated with common traits; however, a great deal of the heritable variation associated with common traits remains unaccounted for within the genome. Genome-wide complex trait...

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主要な著者: Keller, Margaux F., Saad, Mohamad, Bras, Jose, Bettella, Francesco, Nicolaou, Nayia, Simón-Sánchez, Javier, Mittag, Florian, Büchel, Finja, Sharma, Manu, Gibbs, J. Raphael, Schulte, Claudia, Moskvina, Valentina, Durr, Alexandra, Holmans, Peter, Kilarski, Laura L., Guerreiro, Rita, Hernandez, Dena G., Brice, Alexis, Ylikotila, Pauli, Stefánsson, Hreinn, Majamaa, Kari, Morris, Huw R., Williams, Nigel, Gasser, Thomas, Heutink, Peter, Wood, Nicholas W., Hardy, John, Martinez, Maria, Singleton, Andrew B., Nalls, Michael A.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576713/
https://ncbi.nlm.nih.gov/pubmed/22892372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds335
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