Using genome-wide complex trait analysis to quantify ‘missing heritability’ in Parkinson's disease

Genome-wide association studies (GWASs) have been successful at identifying single-nucleotide polymorphisms (SNPs) highly associated with common traits; however, a great deal of the heritable variation associated with common traits remains unaccounted for within the genome. Genome-wide complex trait...

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Xehetasun bibliografikoak
Egile Nagusiak: Keller, Margaux F., Saad, Mohamad, Bras, Jose, Bettella, Francesco, Nicolaou, Nayia, Simón-Sánchez, Javier, Mittag, Florian, Büchel, Finja, Sharma, Manu, Gibbs, J. Raphael, Schulte, Claudia, Moskvina, Valentina, Durr, Alexandra, Holmans, Peter, Kilarski, Laura L., Guerreiro, Rita, Hernandez, Dena G., Brice, Alexis, Ylikotila, Pauli, Stefánsson, Hreinn, Majamaa, Kari, Morris, Huw R., Williams, Nigel, Gasser, Thomas, Heutink, Peter, Wood, Nicholas W., Hardy, John, Martinez, Maria, Singleton, Andrew B., Nalls, Michael A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2012
Gaiak:
Association Studies Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576713/
https://ncbi.nlm.nih.gov/pubmed/22892372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds335
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