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Stochastic Model-Assisted Development of Efficient Low-Dose Viral Transduction in Microfluidics

Adenoviruses are commonly used in vitro as gene transfer vectors in multiple applications. Nevertheless, issues such as low infection efficiency and toxicity effects on host cells have not been resolved yet. This work aims at developing a new versatile tool to enhance the expression of transduced ge...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Luni, Camilla, Michielin, Federica, Barzon, Luisa, Calabrò, Vincenza, Elvassore, Nicola
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576536/
https://ncbi.nlm.nih.gov/pubmed/23442972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.049
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