Low Percentage of KRAS Mutations Revealed by Locked Nucleic Acid Polymerase Chain Reaction: Implications for Treatment of Metastatic Colorectal Cancer

Metastatic colorectal cancer (mCRC) is frequently characterized by the presence of mutations of the KRAS oncogene, which are generally associated with a poor response to treatment with anti-epidermal growth factor receptor (anti-EGFR) monoclonal antibodies. With the methods currently used, a case is...

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Detalhes bibliográficos
Main Authors: Dono, Mariella, Massucco, Carlotta, Chiara, Silvana, Sonaglio, Claudia, Mora, Marco, Truini, Anna, Cerruti, Giannamaria, Zoppoli, Gabriele, Ballestrero, Alberto, Truini, Mauro, Ferrarini, Manlio, Zupo, Simona
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576474/
https://ncbi.nlm.nih.gov/pubmed/23255073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00175
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