Proton NMR-Based Metabolite Analyses of Archived Serial Paired Serum and Urine Samples from Myeloma Patients at Different Stages of Disease Activity Identifies Acetylcarnitine as a Novel Marker of Active Disease

BACKGROUND: Biomarker identification is becoming increasingly important for the development of personalized or stratified therapies. Metabolomics yields biomarkers indicative of phenotype that can be used to characterize transitions between health and disease, disease progression and therapeutic res...

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Detalhes bibliográficos
Main Authors: Lodi, Alessia, Tiziani, Stefano, Khanim, Farhat L., Günther, Ulrich L., Viant, Mark R., Morgan, Gareth J., Bunce, Christopher M., Drayson, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576408/
https://ncbi.nlm.nih.gov/pubmed/23431376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056422
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