A Decreased Level of Serum Soluble Klotho Is an Independent Biomarker Associated with Arterial Stiffness in Patients with Chronic Kidney Disease

BACKGROUND: Klotho was originally identified in a mutant mouse strain unable to express the gene that consequently showed shortened life spans. In humans, low serum Klotho levels are related to the prevalence of cardiovascular diseases in community-dwelling adults. However, it is unclear whether the...

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Detalhes bibliográficos
Main Authors: Kitagawa, Masashi, Sugiyama, Hitoshi, Morinaga, Hiroshi, Inoue, Tatsuyuki, Takiue, Keiichi, Ogawa, Ayu, Yamanari, Toshio, Kikumoto, Yoko, Uchida, Haruhito Adam, Kitamura, Shinji, Maeshima, Yohei, Nakamura, Kazufumi, Ito, Hiroshi, Makino, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576368/
https://ncbi.nlm.nih.gov/pubmed/23431388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056695
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