Suppression of Adiponectin by Aberrantly Glycosylated IgA1 in Glomerular Mesangial Cells In Vitro and In Vivo

The pathogenesis of IgA nephropathy (IgAN) may be associated with the mesangial deposition of aberrantly glycosylated IgA1. To identify mediators affected by aberrantly glycosylated IgA1 in cultured human mesangial cells (HMCs), we generated enzymatically modified desialylated and degalactosylated (...

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Detalhes bibliográficos
Main Authors: Inoue, Tatsuyuki, Sugiyama, Hitoshi, Kitagawa, Masashi, Takiue, Keiichi, Morinaga, Hiroshi, Ogawa, Ayu, Kikumoto, Yoko, Kitamura, Shinji, Maeshima, Yohei, Makino, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311555/
https://ncbi.nlm.nih.gov/pubmed/22457806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033965
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