Epithelial–Mesenchymal Transition (EMT) Induced by TNF-α Requires AKT/GSK-3β-Mediated Stabilization of Snail in Colorectal Cancer

Chronic inflammation-promoted metastasis has been considered as a major challenge in cancer therapy. Pro-inflammatory cytokine TNFα can induce cancer invasion and metastasis associated with epithelial–mesenchymal transition (EMT). However, the underlying mechanisms are not entirely clear. In this st...

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Detalhes bibliográficos
Main Authors: Wang, Hao, Wang, Hong-Sheng, Zhou, Bin-Hua, Li, Cui-Lin, Zhang, Fan, Wang, Xian-Feng, Zhang, Ge, Bu, Xian-Zhang, Cai, Shao-Hui, Du, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576347/
https://ncbi.nlm.nih.gov/pubmed/23431386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056664
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