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The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model

BACKGROUND: Acetaminophen (N-acetyl-para-aminophenol) is the most widely used over-the-counter or prescription painkiller in the world. Acetaminophen is metabolized in the liver where a toxic byproduct is produced that can be removed by conjugation with glutathione. Acetaminophen overdoses, either a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ben-Shachar, Rotem, Chen, Yifei, Luo, Shishi, Hartman, Catherine, Reed, Michael, Nijhout, H Frederik
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576299/
https://ncbi.nlm.nih.gov/pubmed/23249634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-9-55
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