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The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model
BACKGROUND: Acetaminophen (N-acetyl-para-aminophenol) is the most widely used over-the-counter or prescription painkiller in the world. Acetaminophen is metabolized in the liver where a toxic byproduct is produced that can be removed by conjugation with glutathione. Acetaminophen overdoses, either a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3576299/ https://ncbi.nlm.nih.gov/pubmed/23249634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-9-55 |
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