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Silencing of B7-H3 increases gemcitabine sensitivity by promoting apoptosis in pancreatic carcinoma

In numerous types of cancer, the expression of a novel member of the B7 ligand family, the B7-H3 immunoregulatory protein, has been correlated with a poor prognosis. In the present study, we investigated the role of B7-H3 in chemoresistance in pancreatic carcinoma. Silencing of B7-H3, through lentiv...

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Bibliografiske detaljer
Main Authors: ZHAO, XIN, ZHANG, GUANG-BO, GAN, WEN-JUAN, XIONG, FENG, LI, ZHI, ZHAO, HUA, ZHU, DONG-MING, ZHANG, BIN, ZHANG, XUE-GUANG, LI, DE-CHUN
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576185/
https://ncbi.nlm.nih.gov/pubmed/23426281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2013.1118
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