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Mitochondrial Glutathione Transport Is a Key Determinant of Neuronal Susceptibility to Oxidative and Nitrosative Stress

Mitochondrial oxidative stress significantly contributes to the underlying pathology of several devastating neurodegenerative disorders. Mitochondria are highly sensitive to the damaging effects of reactive oxygen and nitrogen species; therefore, these organelles are equipped with a number of free r...

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מידע ביבליוגרפי
Main Authors: Wilkins, Heather M., Kirchhof, Danielle, Manning, Evan, Joseph, Jamie W., Linseman, Daniel A.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576114/
https://ncbi.nlm.nih.gov/pubmed/23283974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.405738
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