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Determination of amyloid core structure using chemical shifts

Amyloid fibrils are the pathological hallmark of a large variety of neurodegenerative disorders. The structural characterization of amyloid fibrils, however, is challenging due to their non-crystalline, heterogeneous, and often dynamic nature. Thus, the structure of amyloid fibrils of many proteins...

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Hlavní autoři: Skora, Lukasz, Zweckstetter, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., A Wiley Company 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575924/
https://ncbi.nlm.nih.gov/pubmed/23033250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2170
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