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Age-dependent racemization of serine residues in a human chaperone protein

Racemization is one of the most abundant modifications in long-lived proteins. It has been proposed that the accumulation of such modifications over time could lead to changes in tissues and ultimately human age-related diseases. Serine is one of the main amino acids involved in racemization; howeve...

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Autores principales: Hooi, Michelle Y S, Raftery, Mark J, Truscott, Roger J W
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575864/
https://ncbi.nlm.nih.gov/pubmed/23139182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2191
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