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Racemisation and human cataract. d-Ser, d-Asp/Asn and d-Thr are higher in the lifelong proteins of cataract lenses than in age-matched normal lenses

Several amino acids were found to undergo progressive age-dependent racemisation in the lifelong proteins of normal human lenses. The two most highly racemised were Ser and Asx. By age 70, 4.5% of all Ser residues had been racemised, along with >9% of Asx residues. Such a high level of inversion,...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Hooi, Michelle Yu Sung, Truscott, Roger J. W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Netherlands 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127471/
https://ncbi.nlm.nih.gov/pubmed/20686926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-010-9171-7
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