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Ser(95), Asn(97), and Thr(78) are important for the catalytic function of porcine NADP-dependent isocitrate dehydrogenase
The mammalian mitochondrial NADP-dependent isocitrate dehydrogenase is a citric acid cycle enzyme and an important contributor to cellular defense against oxidative stress. The Mn(2+)-isocitrate complex of the porcine enzyme was recently crystallized; its structure indicates that Ser(95), Asn(97), a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253315/ https://ncbi.nlm.nih.gov/pubmed/15576556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041091805 |
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