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Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage
The E3 ubiquitin ligase Rad18 mediates tolerance of replication fork-stalling bulky DNA lesions, but whether Rad18 mediates tolerance of bulky DNA lesions acquired outside S-phase is unclear. Using synchronized cultures of primary human cells, we defined cell cycle stage-specific contributions of Ra...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3575850/ https://ncbi.nlm.nih.gov/pubmed/23295675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1325 |
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