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De novo design of a synthetic riboswitch that regulates transcription termination

Riboswitches are regulatory RNA elements typically located in the 5′-untranslated region of certain mRNAs and control gene expression at the level of transcription or translation. These elements consist of a sensor and an adjacent actuator domain. The sensor usually is an aptamer that specifically i...

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Détails bibliographiques
Auteurs principaux: Wachsmuth, Manja, Findeiß, Sven, Weissheimer, Nadine, Stadler, Peter F., Mörl, Mario
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2013
Sujets:
RNA
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575828/
https://ncbi.nlm.nih.gov/pubmed/23275562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1330
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