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Ligand-dependent tRNA processing by a rationally designed RNase P riboswitch
We describe a synthetic riboswitch element that implements a regulatory principle which directly addresses an essential tRNA maturation step. Constructed using a rational in silico design approach, this riboswitch regulates RNase P-catalyzed tRNA 5′-processing by either sequestering or exposing the...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7897497/ https://ncbi.nlm.nih.gov/pubmed/33469651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1282 |
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