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Transcription-independent role for human mitochondrial RNA polymerase in mitochondrial ribosome biogenesis

Human mitochondrial RNA polymerase, POLRMT, is required for mitochondrial DNA (mtDNA) transcription and forms initiation complexes with human mitochondrial transcription factor B2 (h-mtTFB2). However, POLRMT also interacts with the paralogue of h-mtTFB2, h-mtTFB1, which is a 12S ribosomal RNA methyl...

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Main Authors: Surovtseva, Yulia V., Shadel, Gerald S.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575816/
https://ncbi.nlm.nih.gov/pubmed/23303773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1447
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