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Antibody repertoire development in fetal and neonatal piglets. XVI. Influenza stimulates adaptive immunity, class switch and diversification of the IgG repertoire encoded by downstream Cγ genes

Infection of germ-free isolator piglets with swine influenza (S-FLU) that generates dsRNA during replication causes elevation of immunoglobulins in serum and bronchoalveolar lavage, a very weak response to trinitrophenyl conjugates but an immune response to S-FLU. The increased immunoglobulin levels...

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Bibliografiske detaljer
Main Authors: Butler, John E, Sun, XiuZhu, Wertz, Nancy, Vincent, Amy L, Zanella, Eraldo L, Lager, Kelly M
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575766/
https://ncbi.nlm.nih.gov/pubmed/23320646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12018
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