The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells

Myeloid-derived suppressor cells (MDSC) and regulatory T (Treg) cells are major components of the immune suppressive tumour microenvironment (TME). Both cell types expand systematically in preclinical tumour models and promote T-cell dysfunction that in turn favours tumour progression. Clinical repo...

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Main Authors: Lindau, Dennis, Gielen, Paul, Kroesen, Michiel, Wesseling, Pieter, Adema, Gosse J
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2013
Assuntos:
Review Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575763/
https://ncbi.nlm.nih.gov/pubmed/23216602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12036
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