Zasp regulates integrin activation

Integrins are heterodimeric adhesion receptors that link the extracellular matrix (ECM) to the cytoskeleton. Binding of the scaffold protein, talin, to the cytoplasmic tail of β-integrin causes a conformational change of the extracellular domains of the integrin heterodimer, thus allowing high-affin...

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Bibliografiske detaljer
Main Authors: Bouaouina, Mohamed, Jani, Klodiana, Long, Jenny Y., Czerniecki, Stefan, Morse, Elizabeth M., Ellis, Stephanie J., Tanentzapf, Guy, Schöck, Frieder, Calderwood, David A.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575701/
https://ncbi.nlm.nih.gov/pubmed/22992465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.103291
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