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Vector-Mediated Selective Expression of Lethal Factor, a Toxic Element of Bacillus Anthracis, Damages A549 Cells via Inhibition of MAPK and AKT Pathways

Lethal factor (LF), a major toxic element of Bacillus anthracis combined with its protective antigen (PA), enters the cells through the cytomembrane receptors and causes damage to the host cells, thereby leading to septicemia, toxemia, and meningitis with high mortality. LF has been identified as a...

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Detalhes bibliográficos
Main Authors: Zhuo, Wenlei, Tao, Guangli, Zhang, Liang, Chen, Zhengtang
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575624/
https://ncbi.nlm.nih.gov/pubmed/23423542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.5570
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