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A Bacterial Artificial Chromosome Transgene with Polymorphic Cd72 Inhibits the Development of Glomerulonephritis and Vasculitis in MRL-Fas(lpr) Lupus Mice

Systemic lupus erythematosus is considered to be under the control of polygenic inheritance, developing according to the cumulative effects of susceptibility genes with polymorphic alleles; however, the mechanisms underlying the roles of polygenes based on functional and pathological genomics remain...

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Detalhes bibliográficos
Main Authors: Oishi, Hisashi, Tsubaki, Takahito, Miyazaki, Tatsuhiko, Ono, Masao, Nose, Masato, Takahashi, Satoru
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575566/
https://ncbi.nlm.nih.gov/pubmed/23365086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202196
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