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Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin

Although Wnt signaling is considered a key regulatory pathway for bone formation, inactivation of β-catenin in osteoblasts does not affect their activity but rather causes increased osteoclastogenesis due to insufficient production of osteoprotegerin (Opg). By monitoring the expression pattern of al...

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Autori principali: Albers, Joachim, Keller, Johannes, Baranowsky, Anke, Beil, Frank Timo, Catala-Lehnen, Philip, Schulze, Jochen, Amling, Michael, Schinke, Thorsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575535/
https://ncbi.nlm.nih.gov/pubmed/23401003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207142
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