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Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin
Although Wnt signaling is considered a key regulatory pathway for bone formation, inactivation of β-catenin in osteoblasts does not affect their activity but rather causes increased osteoclastogenesis due to insufficient production of osteoprotegerin (Opg). By monitoring the expression pattern of al...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3575535/ https://ncbi.nlm.nih.gov/pubmed/23401003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207142 |
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