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OX40 engagement stabilizes Mxd4 and Mnt protein levels in antigen-stimulated T cells leading to an increase in survival
OX40 engagement on activated T cells leads to increased proliferation, expansion and survival of Ag-specific T cells. Here we show that the Myc antagonists, Mxd4 and Mnt are transiently upregulated and translocated to the nucleus following OX40 engagement and may be involved in suppressing cell deat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3575515/ https://ncbi.nlm.nih.gov/pubmed/21400495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040449 |
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