Multiple Cationic Amphiphiles Induce a Niemann-Pick C Phenotype and Inhibit Ebola Virus Entry and Infection

Ebola virus (EBOV) is an enveloped RNA virus that causes hemorrhagic fever in humans and non-human primates. Infection requires internalization from the cell surface and trafficking to a late endocytic compartment, where viral fusion occurs, providing a conduit for the viral genome to enter the cyto...

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Autors principals: Shoemaker, Charles J., Schornberg, Kathryn L., Delos, Sue E., Scully, Corinne, Pajouhesh, Hassan, Olinger, Gene G., Johansen, Lisa M., White, Judith M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575416/
https://ncbi.nlm.nih.gov/pubmed/23441171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056265
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