Human Concentrative Nucleoside Transporter 3 Transfection with Ultrasound and Microbubbles in Nucleoside Transport Deficient HEK293 Cells Greatly Increases Gemcitabine Uptake

Gemcitabine is a hydrophilic clinical anticancer drug that requires nucleoside transporters to cross plasma membranes and enter cells. Pancreatic adenocarcinomas with low levels of nucleoside transporters are generally resistant to gemcitabine and are currently a clinical problem. We tested whether...

Full description

Saved in:
Bibliographic Details
Main Authors: Paproski, Robert J., Yao, Sylvia Y. M., Favis, Nicole, Evans, David, Young, James D., Cass, Carol E., Zemp, Roger J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575408/
https://ncbi.nlm.nih.gov/pubmed/23441192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056423
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items