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Genomic EWS-FLI1 Fusion Sequences in Ewing Sarcoma Resemble Breakpoint Characteristics of Immature Lymphoid Malignancies

Chromosomal translocations between the EWS gene and members of the ETS gene family are characteristic molecular features of the Ewing sarcoma. The most common translocation t(11;22)(q24;q12) fuses the EWS gene to FLI1, and is present in 85–90% of Ewing sarcomas. In the present study, a specifically...

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Detaylı Bibliyografya
Asıl Yazarlar: Berger, Manfred, Dirksen, Uta, Braeuninger, Andreas, Koehler, Gabriele, Juergens, Heribert, Krumbholz, Manuela, Metzler, Markus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575406/
https://ncbi.nlm.nih.gov/pubmed/23441188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056408
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