Genomic EWS-FLI1 Fusion Sequences in Ewing Sarcoma Resemble Breakpoint Characteristics of Immature Lymphoid Malignancies

Chromosomal translocations between the EWS gene and members of the ETS gene family are characteristic molecular features of the Ewing sarcoma. The most common translocation t(11;22)(q24;q12) fuses the EWS gene to FLI1, and is present in 85–90% of Ewing sarcomas. In the present study, a specifically...

詳細記述

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書誌詳細
主要な著者: Berger, Manfred, Dirksen, Uta, Braeuninger, Andreas, Koehler, Gabriele, Juergens, Heribert, Krumbholz, Manuela, Metzler, Markus
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575406/
https://ncbi.nlm.nih.gov/pubmed/23441188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056408
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