Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia

BACKGROUND: Hypoxia induces microglial activation which causes damage to the developing brain. Microglia derived inflammatory mediators may contribute to this process. Toll-like receptor 4 (TLR4) has been reported to induce microglial activation and cytokines production in brain injuries; however, i...

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Detalhes bibliográficos
Main Authors: Yao, Linli, Kan, Enci Mary, Lu, Jia, Hao, Aijun, Dheen, S Thameem, Kaur, Charanjit, Ling, Eng-Ang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575244/
https://ncbi.nlm.nih.gov/pubmed/23388509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-23
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