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Cyanide Antidotes for Mass Casualties: Water-Soluble Salts of the Dithiane (Sulfanegen) from 3-Mercaptopyruvate for Intramuscular Administration

Current cyanide antidotes are administered by IV infusion which is suboptimal for mass casualties. Therefore, in a cyanide disaster intramuscular (IM) injectable antidotes would be more appropriate. We report the discovery of the highly water-soluble sulfanegen triethanolamine as a promising lead fo...

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Detalhes bibliográficos
Main Authors: Patterson, Steven E., Monteil, Alexandre R., Cohen, Jonathan F., Crankshaw, Daune L., Vince, Robert, Nagasawa, Herbert T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575131/
https://ncbi.nlm.nih.gov/pubmed/23301495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301633x
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