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Treatment of hemophilia B: focus on recombinant factor IX

Hemophilia B is a recessive X-linked bleeding disorder characterized by deficiency of the coagulation factor IX (FIX). In hemophilia B patients the severity of the bleeding phenotype is related to the degree of the FIX defect. Hemophilia B treatment has improved greatly in the last 20 years with the...

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Hlavní autoři: Franchini, Massimo, Frattini, Francesco, Crestani, Silvia, Sissa, Cinzia, Bonfanti, Carlo
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575125/
https://ncbi.nlm.nih.gov/pubmed/23430394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S31582
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