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Differential state-dependent modification of inactivation-deficient Na(v)1.6 sodium channels by the pyrethroid insecticides S-bioallethrin, tefluthrin and deltamethrin
Pyrethroid insecticides disrupt nerve function by modifying the gating kinetics of transitions between the conducting and nonconducting states of voltage-gated sodium channels. Pyrethroids modify rat Na(v)1.6 + β1 + β2 channels expressed in Xenopus oocytes in both the resting state and in one or mor...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3574822/ https://ncbi.nlm.nih.gov/pubmed/22465659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2012.03.007 |
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