Cognitive Enhancement with Rosiglitazone Links the Hippocampal PPARγ and ERK MAPK Signaling Pathways

We previously reported that the peroxisome proliferator-activated receptor γ (PPARγ) agonist rosiglitazone (RSG) improved hippocampus-dependent cognition in the Alzheimer's disease (AD) mouse model, Tg2576. RSG had no effect on wild-type littermate cognitive performance. Since extracellular sig...

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Detalhes bibliográficos
Main Authors: Denner, Larry A., Rodriguez-Rivera, Jennifer, Haidacher, Sigmund J., Jahrling, Jordan B., Carmical, J. Russ, Hernandez, Caterina M., Zhao, Yingxin, Sadygov, Rovshan G., Starkey, Jonathan M., Spratt, Heidi, Luxon, Bruce A., Wood, Thomas G., Dineley, Kelly T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574637/
https://ncbi.nlm.nih.gov/pubmed/23175826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2153-12.2012
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