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Viral mutation rates: modelling the roles of within-host viral dynamics and the trade-off between replication fidelity and speed
Many viruses, particularly RNA viruses, mutate at a very high rate per genome per replication. One possible explanation is that high mutation rates are selected to meet the challenge of fluctuating environments, including the host immune response. Alternatively, recent studies argue that viruses evo...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Royal Society
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3574426/ https://ncbi.nlm.nih.gov/pubmed/23135674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2012.2047 |
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