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Iron oxide nanoparticles as a clinically acceptable delivery platform for a recombinant blood-stage human malaria vaccine

This study explored the novel use of iron oxide (IO) nanoparticles (<20 nm) as a vaccine delivery platform without additional adjuvants. A recombinant malaria vaccine antigen, the merozoite surface protein 1 (rMSP1), was conjugated to IO nanoparticles (rMSP1-IO). Immunizations in outbred mice wit...

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Detalhes bibliográficos
Main Authors: Pusic, Kae, Aguilar, Zoraida, McLoughlin, Jaclyn, Kobuch, Sophie, Xu, Hong, Tsang, Mazie, Wang, Andrew, Hui, George
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574285/
https://ncbi.nlm.nih.gov/pubmed/23195035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-218362
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