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Blood Stage Merozoite Surface Protein Conjugated to Nanoparticles Induce Potent Parasite Inhibitory Antibodies

In this proof-of-concept study we report the use of <15nm, water soluble, inorganic nanoparticles as a vaccine delivery system for a blood stage malaria vaccine. The recombinant malarial antigen, Merozoite Surface Protein 1 (rMSP1) of P. falciparum served as the model vaccine. The rMSP1 was coval...

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Hlavní autoři: Pusic, Kae, Xu, Hengyi, Stridiron, Andrew, Aguilar, Zoraida, Wang, Andrew, Hui, George
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202662/
https://ncbi.nlm.nih.gov/pubmed/21963870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.09.070
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