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Gpr177 Deficiency Impairs Mammary Development and Prohibits Wnt-Induced Tumorigenesis

Aberrant regulation of the Wnt pathway, essential for various developmental processes, is tightly linked to human breast cancers. By hijacking this evolutionary conserved signaling pathway, cancer cells acquire sustaining proliferation ability, leading to modification of physiologic properties neces...

詳細記述

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書誌詳細
主要な著者: Maruyama, Eri Ohfuchi, Yu, H-M. Ivy, Jiang, Ming, Fu, Jiang, Hsu, Wei
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574013/
https://ncbi.nlm.nih.gov/pubmed/23457599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056644
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