Gpr177 Deficiency Impairs Mammary Development and Prohibits Wnt-Induced Tumorigenesis

Aberrant regulation of the Wnt pathway, essential for various developmental processes, is tightly linked to human breast cancers. By hijacking this evolutionary conserved signaling pathway, cancer cells acquire sustaining proliferation ability, leading to modification of physiologic properties neces...

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Bibliographic Details
Main Authors: Maruyama, Eri Ohfuchi, Yu, H-M. Ivy, Jiang, Ming, Fu, Jiang, Hsu, Wei
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574013/
https://ncbi.nlm.nih.gov/pubmed/23457599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056644
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