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A New Glucocorticoid Hypothesis of Brain Aging: Implications for Alzheimer’s Disease

The original glucocorticoid (GC) hypothesis of brain aging and Alzheimer’s disease proposed that chronic exposure to GCs promotes hippocampal aging and AD. This proposition arose from a study correlating increasing plasma corticosterone with hippocampal astrocyte reactivity in aging rats. Numerous s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Landfield, Philip W., Blalock, Eric M., Chen, Kuey-Chu, Porter, Nada M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573879/
https://ncbi.nlm.nih.gov/pubmed/17430248
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