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PKC-θ and the immunological synapse: mechanisms and implications

Protein kinase C-θ has emerged as a central regulator of conventional effector T cell (Teff) and CD4(+)FoxP3(+) regulatory T cell (Treg) function. In the years since this initial description PKC-θ regulation has taken on even greater complexity, as it has been implicated in negative regulation of im...

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Bibliografiske detaljer
Main Authors: Zanin-Zhorov, Alexandra, Dustin, Michael L, Blazar, Bruce R.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573858/
https://ncbi.nlm.nih.gov/pubmed/21733754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2011.04.007
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