Anti-dyskinetic mechanisms of amantadine and dextromethorphan in the 6-OHDA rat model of Parkinson’s disease: role of NMDA vs. 5-HT1A receptors

Amantadine and dextromethorphan suppress levodopa (L-DOPA)-induced dyskinesia (LID) in patients with Parkinson’s disease (PD) and abnormal involuntary movements (AIMs) in the unilateral 6-hydroxydopamine (6-OHDA) rat model. These effects have been attributed to N-methyl-d-aspartate (NMDA) antagonism...

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Detaylı Bibliyografya
Asıl Yazarlar: Paquette, Melanie A., Martinez, Alex A., Macheda, Teresa, Meshul, Charles K., Johnson, Steven W., Berger, S. Paul, Giuffrida, Andrea
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573705/
https://ncbi.nlm.nih.gov/pubmed/22861201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2012.08243.x
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