MK-801 inhibits L-DOPA-induced abnormal involuntary movements only at doses that worsen parkinsonism

Amantadine and dextromethorphan suppress levodopa (L-DOPA)-induced dyskinesia in Parkinson's disease patients and abnormal involuntary movements (AIM) in the 6-hydroxydopamine (6-OHDA) rat model. These medications have been hypothesized to exert their therapeutic effects by a noncompetitive N-m...

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Detalhes bibliográficos
Main Authors: Paquette, Melanie A., Anderson, Akari M., Lewis, Jason R., Meshul, Charles K., Johnson, Steven W., Berger, S. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849839/
https://ncbi.nlm.nih.gov/pubmed/20079362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.01.003
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